Linear Polyethylenimine (PEI) for Transfection | Curapath

Linear Polyethylenimine (PEI)

Linear PEI for transfection, viral vector production and recombinant protein expression. Available in R&D and GMP grades, with scalable manufacturing and powder or solution formats.

Linear polyethylenimine (PEI) chemical structure
Linear PEI · MW 20,000

About Curapath® PEI 

Curapath® PEI (linear polyethylenimine Hydrochloride, MW 20,000 Da) forms stable complexes with DNA, supporting efficient nucleic acid delivery in applications ranging from in vitro cell transfection to viral vector production and recombinant protein expression.

Available as a dry form or solution in R&D and GMP grades, Curapath PEI® supports the transition from process development to clinical and commercial manufacturing. Its optimized formulation enables high-titer vector and recombinant protein production while maintaining cell viability, offering a reliable and scalable alternative to conventional PEI-based transfection reagents.

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Applications

Commonly Used For

Linear PEI is a versatile transfection reagent widely used in research, process development, and bioproduction workflows. It is particularly valuable for plasmid delivery in mammalian cells, supporting both exploratory R&D and scalable upstream applications.

Transient Expression and Stable Cell Line Development

PEI is commonly used for transient transfection in mammalian cells and for the generation of stable producer cell lines, enabling efficient gene delivery during early discovery and cell line development workflows.

Co-Transfection and Sequential Transfection Workflows

Its flexibility makes PEI suitable for co-transfection strategies and sequential transfection protocols, helping researchers introduce multiple plasmids or optimize multistep expression workflows in vitro.

AAV and Lentiviral Vector Production

PEI is widely adopted for plasmid delivery during AAV and lentiviral vector production, supporting efficient transfection of producer cells in workflows used for gene therapy and advanced therapy development.

Recombinant Protein and Monoclonal Antibody (mAb) Expression

PEI is frequently used in recombinant protein and monoclonal antibody expression systems, offering a practical and scalable option for upstream transfection in biologics development and production.

Product request

Request Curapath® PEI

Select the Curapath PEI® format that best fits your application and submit the corresponding product request. Our team will review your requirements and contact you directly.

Dry format

Request Dry Curapath® PEI

Complete the form below to request Curapath PEI® in dry format. Our team will review your application, grade and supply requirements.